Research progress in immunotherapy of advanced non-small cell lung cancer
نویسندگان
چکیده
Non-small cell lung cancer (NSCLC) poses a serious threat to people’s health. Its morbidity and mortality are among the highest all malignant tumors, there is an urgent need for more effective new treatment methods. In recent years, NSCLC immunotherapy has made great progress, first PD-1 inhibitor nivolumab (Nivolumab, O drug) was approved by US Food Drug Administration (FDA) in March 2015, applying patients who progressed or received platinum chemotherapy drugs past. Immunotherapy of advanced entered era. This article reviews current research progress immunotherapy.
منابع مشابه
[Progress in immunotherapy for non-small cell lung cancer].
In recent years, the five-year survival rate of patients with advanced stage non-small cell lung cancer (NSCLC) remains low despite recent advances in surgery, irradiation, chemotherapy, and targeted therapy. Immunotherapy which utilizes the immune system to control and eradicate cancer is a viable treatment approach for malignancy. Immunotherapy in patients with lung cancer has made breakthrou...
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Lung cancer is the leading cause of cancer-related mortality worldwide, and more than 80% of cases are of non-small cell lung cancer. Although chemotherapy and molecularly targeted therapy may provide some benefit, there is a need for newer therapies for the treatment of patients with advanced NSCLC. Immunotherapy aims to augment the recognition of cancer as foreign, to stimulate immune respons...
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cisplatin-based chemotherapy is the standard treatment for advanced non-small cell lung cancer (nsclc). many novel drugs have been used in combination with cisplatin in this setting. of these drugs, gemcitabine is reported to have a high response rate and acceptable toxicity. the aim of this study was to evaluate the efficacy and safety of gemcitabine and cisplatin combination. twentythree pati...
متن کاملphase ii study of gemcitabine and cisplatin regimen in advanced non-small cell lung cancer (nsclc).
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متن کاملImmunotherapy in the treatment of non-small cell lung cancer.
Advances in the understanding of the role of the immune system in tumor immunosurveillance have resulted in the recognition that tumors can evade immune destruction via the dysregulation of co-inhibitory or checkpoint signals. This has led to the development of a generation immunotherapeutic agents targeting the immune checkpoint pathway. Recent early phase studies of immune checkpoint modulato...
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ژورنال
عنوان ژورنال: Trends in immunotherapy
سال: 2021
ISSN: ['2573-5985']
DOI: https://doi.org/10.24294/ti.v5.i2.1.1367